Vertical-Wheel FLUIDIX™ Vessels
Pre-sterilized, single-use Vertical-Wheel FLUIDIX™ Vessels carry the same culture environment from benchtop process development through clinical and commercial manufacturing. Scale working volume from 60mL to 80L while preserving the mixing conditions that make your cells thrive.
Purchase PBS-Mini bases & vessels using the online store.
Built for Cells
The Vertical-Wheel FLUIDIX™ Vessel is more than a container. It is the foundation of a transferable process. Every vessel in the Vertical-Wheel® product family uses the same core geometry, creating comparable mixing, suspension, and mass transfer conditions from development through manufacturing. That means process knowledge gained at small scale remains relevant as production grows.
Gentle, homogeneous hydrodynamic conditions ideal for sheer-sensitive cells promote cell high yield and vitality
One consistent vessel and impeller geometry ensures linear, predicable scalability from 0.1L all the way to 80L.
Settlement media exchange and perfusion for continuous media exchange along with multiple port options and configurations support your specific process needs.
GMP-Research, GMP-Clinical and GMP-Commercial grade vessels support your needs at every stage of development and commercialization.
Gentle, Uniform, and the Same at Every Scale
Cells experience low sheer, no dead zones and the same homogeneous hydrodynamic environment from 60mL to 80L scale — so a process transfers up without being re-developed.
That is made possible by Vertical-Wheel FLUIDIX™: our patent-pending fluid dynamics environment — uniform and predicable energy dissipation and gas transfer — produced by a large vertical impeller turning slowly inside a U-shaped vessel, characterized by CFD studies and held constant across the whole range.
How Vertical-Wheel technology workscGMP-Aligned Vessels for Every Stage of Development
Every Vertical-Wheel Fluidix™ Vessel is manufactured in an ISO 7 cleanroom and comes in three qualification grades. Choose the grade that matches where your development stage, and move up as it advances toward the clinic and commercial supply.
| Testing & Validation | GMP-Research | GMP-Clinical | GMP-Commercial |
|---|---|---|---|
| Biocompatibility | Included | Included | Included |
| Endotoxin | Included | Included | Included |
| Particulates | Included | Included | Included |
| Accelerated Shelf-Life | Included | Included | Included |
| Transport Studies | Included | Included | Included |
| Supplier Qualification & Traceability | Included | Included | Included |
| ISO 7 Cleanroom Manufactured | Included | Included | Included |
| Visual & Leak Test | Included | Included | Included |
| Irradiation | Included | Included | IncludedWith dose audit |
| Extractables | —Not included | —Not included | Included |
| Stability Assurance | —Not included | —Not included | Included |
| Real-Time Stability | —Not included | —Not included | Included |
| Mold & Tooling Validation | —Not included | —Not included | Included |
| Process Verification | —Not included | —Not included | Included |
| Process Qualification | —Not included | —Not included | Included |
Vertical-Wheel FLUIDIX™ Vessels for All Scales
| System | Working volume | Vessel | Regulatory grade | How to order |
|---|---|---|---|---|
| PBS-Mini | 60mL–0.5L | Vertical-Wheel FLUIDIX™ 0.1L & 0.5L Vessels | GMP-Research · GMP-Clinical | Buy online |
| PBS-MiniPRO | 0.3-0.5L | Vertical-Wheel FLUIDIX™ 0.5L PRO Vessels | GMP-Research · GMP-Clinical | Request quote |
| PBS-3 | 1.8–3L | Vertical-Wheel FLUIDIX™ 3L Vessels | GMP-Research · GMP-Commercial | Request quote |
| PBS-15 | 9–15L | Vertical-Wheel FLUIDIX™ 15L Vessels | GMP-Research · GMP-Clinical | Request quote |
| PBS-80 | 45–80L | Vertical-Wheel FLUIDIX™ 80L Vessels | GMP-Research | Request quote |
Go Vertical, Today
Tell us what you need and we’ll take it from there.