PBS-0.5 Mini Vertical-Wheel Bioreactor

The PBS-0.5 Mini single use bioreactor is compatible with 300mL– 500mL working sample volumes and the best starting point for optimizing cell therapies by leveraging the benefits of vertical-wheel mixing that can be easily scaled up for larger sample volumes.

Removable caps on single-use vessels allow for sterile liquid handling in biosafety hood
Product contact materials meet regulatory requirements for first-in-human clinical trials
Universal base unit is compatible with single-use vessels

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PBS-0.5 Mini Vertical-Wheel Resources

Product Type	Product	Product Number
Base Unit	PBS-Mini Vertical-Wheel Bioreactor Base Unit (120-240 V)	FA-UNI-B-501
Single-Use Vessels	PBS-0.5 Vertical-Wheel Single-Use Vessel with Bottom Port (pack of 1)	FA-0.5-D-101
Single-Use Vessels	PBS-0.5 Vertical-Wheel Single-Use Vessel (pack of 4)	FA-0.5-D-001
Accessories	PBS-Mini Extended 4-Gang DC Power Distribution Cable	IA-UNI-BA-112

Working volume range:	100 - 500 mL (For liquid mixing) 300 - 500 mL (For cell culture)
Number of ports	2
Gassing	Diffusion through 0.22 micron filter on vent cap
iquid transfer	Port with screw-on vent cap
Product contact materials	Meet requirements for USP Class VI Testing for Plastics and/or ISO 10993

Download Full Technical Spec Sheet

Application Note Title
Defined Biomatrices Accelerate MSC Manufacturing Across Scales	Read Now
T Cell Expansion in PBS-Mini Using CellGenix Reagents	Read Now
Overcoming Bioprocess Bottlenecks in the Large-Scale Expansion of High-Quality hiPSC Aggregates in Vertical-Wheel Stirred Suspension Bioreactors	Read Now
Transcriptome Profiling of Human Pluripotent Stem Cell-Derived Cerebellar Organoids Reveals Faster Commitment Under Dynamic Conditions	Read More
Initial Power Measurements for a Family of Novel Bioreactors	Read More

How can I monitor process parameters during a cell culture run? The 3L bioreactor's software allows for customizable programming of process controls and real-time monitoring of parameters using various sensors. Feedback loops can be used to pause a run based on deviations from a set range.
What are recommended methods for sampling and harvesting? Both sampling and harvesting of cells can be achieved by unscrewing the orange cap on top of the single-use vessel (one cap on 0.1L, two caps on 0.5L vessel) and using a pipette to withdraw media. It is recommended to perform these procedures under a biosafety hood.
What is the function of the power accessory cable? This accessory allows the power cables from four different Mini bases to be combined into one plug for a wall outlet.
What if I have other questions regarding usage or troubleshooting? Please use the Products and/or Service quote form to submit any questions or inquiries related to a specific product(s).
What data are available demonstrating the performance of Vertical-Wheel bioreactors? Our Publications section lists numerous examples of cell culture performance data for various cell types generated by customers and collaborators as well as by our BioLab team.

Title
PBS-Mini User Manual	Read Now
PBS-Mini Datasheet	Read Now

PBS-Mini Single-use bioreactor in the lab

Need Help Maximizing the Yield and Quality of Your Cells?

We can help! Our team of scientists and engineers are well versed in developing cell culture procedures for various types of therapeutic cells using the PBS-0.5 Mini single use bioreactor. We can help with:

Cell separation, washing, and concentration
Rapid medium exchange techniques
Aggregate-based processes including seeding, expansion, differentiation, dissociation, and harvesting

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